Co-Incubation of Human Spermatozoa with Anti-VDAC Antibody Reduced Sperm Motility
نویسندگان
چکیده
منابع مشابه
AB209. Co-incubation of human spermatozoa with anti-VDAC antibody reduced sperm motility
Seminal vesiculitis is the common disease of male urogenital system. However, the pathogenesis of seminal vesiculitis remains unclear. Semenogelin I (Sg I) is mainly synthesized and secreted by seminal vesicle and has antibacterial activity. We thus postulate that Sg I plays an important role during the and development of seminal vesiculitis. In the present study, we analyzed the expression of ...
متن کاملCo-incubation of human spermatozoa with anti-VDAC antibody reduced sperm motility.
BACKGROUND Voltage-dependent anion channel (VDAC), a channel protein, exists in the outer mitochondrial membrane of somatic cells and is involved in multiple physiological and pathophysiological processes. Up until now, little has been known about VDAC in male germ cells. In the present study, the relationship between VDAC and human sperm motility was explored. METHODS Highly motile human spe...
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Voltage-dependent anion channel (VDAC) is mainly located in the mitochondrial outer membrane and participates in many biological processes. In mammals, three VDAC subtypes (VDAC1, 2 and 3) have been identified. Although VDAC has been extensively studied in various tissues and cells, there is little knowledge about the distribution and function of VDAC in male mammalian reproductive system. Seve...
متن کاملHuman mtDNA haplogroups associated with high or reduced spermatozoa motility.
A variety of mtDNA mutations responsible for human diseases have been associated with molecular defects in the OXPHOS system. It has been proposed that mtDNA genetic alterations can also be responsible for sperm dysfunction. In addition, it was suggested that if sperm dysfunction is the main phenotypic consequence, these mutations could be fixed as stable mtDNA variants, because mtDNA is matern...
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Voltage-dependent anion channel (VDAC) is mainly located in the mitochondrial outer membrane and participates in many biological processes. In mammals, three VDAC subtypes (VDAC1, 2 and 3) have been identified. Although VDAC has been extensively studied in various tissues and cells, there is little knowledge about the distribution and function of VDAC in male mammalian reproductive system. Seve...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2014
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000356657